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Neuralgia
Is a painful disorder of the nerves.
Under the general heading of neuralgia are:
► Trigeminal neuralgia (TN)
► Atypical facial pain
► Postherpetic neuralgia (caused by shingles or herpes)
The affected nerves are responsible for sensing touch, temperature sensation and
pressure sensation in the facial area from the jaw to the forehead. The disorder
generally causes short episodes of excruciating pain, usually for less than two
minutes and on only one side of the face. The pain can be described in a variety
of ways such as "stabbing," "sharp," "like lightning," "burning," and even
"itchy".
In the atypical form of TN, the pain can also present as severe or
merely aching and last for extended periods. The pain associated with TN is
recognized as one of the most excruciating pains that can be experienced.
Simple stimuli such as eating, talking, washing the face, or any light touch or
sensation can trigger an attack (even the sensation of a gentle breeze). The
attacks can occur in clusters or as an isolated attack. Some patients will have
a muscle spasm which led to the original term for TN of "tic douleureux" ("tic",
meaning 'spasm', and "douleureux", meaning 'painful', in French).
Neuralgia is a form of chronic pain and can be extremely difficult to diagnose.
Patients usually show no physical abnormalities, and with the attacks generally
lasting a very short time, it can be difficult to reach a doctor before the
attack is over.
Postherpetic neuralgia is the easiest to diagnose because it
follows an obvious cause (shingles).
Neuralgia is rare, especially in those under 30. Women are more likely to be
affected than men, and those over 50 are at the greatest risk. In some cases,
multiple sclerosis is related to nerve damage, causing the pain, so doctors will
likely ask about family history to help diagnose. Nothing unusual can be seen in
brain scans, so diagnosis is usually based on the description of the symptoms.
Medication for seizures has shown promise in managing neuralgia, and some people
have found relief with surgery, though not always permanent relief.
Additional Causes of Neuropathy in Patients with Diabetes
Causes of neuropathy other than the diabetes itself are relatively
common in diabetic patients with distal sensory polyneuropathy. In a
retrospective study of 100 consecutive diabetic patients with
symptomatic neuropathy and often rare features, diabetes accounted for
74% of the neuropathies in the whole group of patients, and for 79% of
those with LDDP. A third of patients had a neuropathy unrelated to
diabetes. Chronic inflammatory demyelinating neuropathy, which was
diagnosed in 9% of the patients, was the most common non-diabetic cause
of neuropathy in this population.
Before attributing a polyneuropathy to diabetes, it is important to
exclude general causes of neuropathy, such as alcoholism, vitamin
deficiency, drug-induced neuropathy,
monoclonal gammopathy,
POEMS syndrome and
amyloidal polyneuropathy.
Pressure palsy seems to be more frequent in diabetic than in
non-diabetic individuals; for example, carpal tunnel syndrome was
reported in 12% of patients with diabetes, compared with 4-5% of
individuals in the general population.
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