F.A.Q. about Angikinase SEDICO (Urokinase 500.000 IU)


How does Angikinase SEDICO is administrated?
Angikinase SEDICO is simply administrated as follow:
The vial is reconstituted in 5 ml saline or sterile water and then diluted in normal saline and given as:
  • Priming infusion dose: 4400 IU / kg at rate of 90 ml / h over 10 minutes
Followed by
  • Continuous infusion dose: 4400 IU/ kg / hour at a rate of 15 ml each hour for 12 - 24 hours
What are the clinical applications of Angikinase SEDICO (Urokinase 500.000 IU)?
Angikinase SEDICO is used clinically as a thrombolytic agent in the treatment of:
  • Pulmonary embolism
  • Severe or massive deep venous thrombosis
  • Recurrent coronary artery thrombosis and Myocardial infarction
  • Peripheral arterial thrombo-embolism
  • Some cases of peritonitis
  • Occluded intravenous or dialysis cannulas

It is also administered intrapleurally to improve the drainage of complicated pleural effusions and empyemas.

Simply, How does Angikinase SEDICO (Urokinase 500.000 IU) work?

Does Angikinase SEDICO effective?
Angikinase SEDICO shows significant reduction of mortality and recurrence of PE:

Konstantinides et Al, 1997