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Amebiasis    

AmebiasisWhat is meant by Amebiasis?
Amebiasis is a parasitic infection caused by Entamoeba histolytica. Amebiasis is an intestinal infection that may or may not be symptomatic. When symptoms are present it is generally known as invasive Amebiasis.

 

How does Amebiasis Transmit?
Amebiasis is usually transmitted by contamination of drinking water and foods with fecal matter, but it can also be transmitted indirectly through contact with dirty hands or objects as well as by sexual intercourse

How to prevent infection with Amebiasis?
Wash hands thoroughly with soap before handling food

 

 

Cleansing vegetablesGood Washing for vegetables and fruits

 

 

Pay attention to toilet seats and taps

 

Does Amebiasis has symptoms & if so what are these symptoms?
Amebiasis may be symptomatic and may be not.

For Symptomatic:
Amebiasis symptoms take from a few days to a few weeks to develop and manifest themselves, but usually it is about two to four weeks. Symptoms can range from mild diarrhea to dysentery with blood and mucus

In Asymptomatic:
Infections the amoeba lives by eating and digesting bacteria and food particles in the gut. It does not usually come in contact with the intestine itself due to the protective layer of mucus that lines the gut. Disease occurs when amoeba comes in contact with the cells lining the intestine. It then secretes the same substances it uses to digest bacteria, which include enzymes that destroy cell membranes and proteins. This process leads to penetration and digestion of human tissues, resulting first in flask-shaped ulcers in the intestine. Entamoeba histolytica ingests the destroyed cells by phagocytosis and is often seen with red blood cells inside
N.B Absence of symptoms or their intensity may vary with such factors as strain of amoeba, immune response of the host, and perhaps associated bacteria and viruses

How does treatment of Amebiasis occur?
Two different sorts of drugs are needed to rid the body of the infection, one for each location.
Metronidazole, is used to destroy ameba that have invaded tissue. It is rapidly absorbed into the bloodstream and transported to the site of infection. Because it is rapidly absorbed there is almost none remaining in the intestine.
Paromomycin or diloxanide furoate is used since most of the amebae remain in the intestine when tissue invasion occurs, it is important to get rid of those also or the patient will be at risk of developing another case of invasive disease.
Therfore first we use Metronidazole then we use paromomycin or diloxanide furoate.

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