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Silymarin
(Tablets)

Composition:Siymarin
Each tablet contains:
Silymarin ...................... 70 mg or 140 mg (Eq. to silybin)

Properties:
Liver damage causes changes in the membrane of the liver cell & in this way impairs the functional capacity of the liver. Silymarin acts as a stabilizer of the liver cell membrane, protects the liver against toxic agents & restores damaged liver cell to normal. It also stimulates kupffer's cell & enhances protein synthesis by acting on ribosomal R.N.A. Thus Silymarin improves the general condition & the digestive function. It increases appetite & body weight & restores liver function to normal. Silymarin is absorbed orally. A major part of Silymarin is excreted via the bile & passes through the enterohepatic circulation. Silymarin is excreted mainly by the kidney although metabolites, particularly sulphate & glucuronide conjugates are also present in bile.
The excretion of Silymarin in humans lasts for about 24 hours & the total amount of Silymarin excreted in bile is about 20-40% of the ingested dose Only 3 - 7 % of the total dose is excreted renally.

Indications:

In acute & chronic hepatitis.
Liver cirrhosis to reduce its progress.
Toxic metabolic liver disorders (alcoholic & diabetic liver degeneration) & other hepatic intoxication.
During administration of drugs hazardous to the liver.

Contra-indications:
No contraindications are so far known when therapeutic doses are administered.

Drug interactions:
Interactions with other drugs are not known.

Dosage and administration:
2 tablets (70 mg) 3 times daily.
1 tablet (140 mg) 3 times daily.

Side effects:
Not reported.

Storage:
Keep at temperature not exceeding 30°C.
Keep medicine out of reach of children.

Packing:
Box of 20 tablets 70 mg.
Box of 20 tablets 140 mg.
Box of 100 strips x 10 tablets 70mg.
Box of 100 strips x 10 tablets 140 mg.

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