Composition: |
 |
Each 5ml contains:
Lactulose................3.35 gm
|
| Properties: |
Sedalac is a synthetic
disaccharide which is poorly absorbed. In
the small intestine, Sedalac is not broken
down by disaccharides and reaches the colon
unchanged where it is degraded by
saccharolytic bacteria into low molecular
organic acids: acetic acid , formic acid,
mainly lactic acid. This results in
acidification of the colonic contents, and
increased osmotic pressure ensuring the
formation of soft stool and the stimulation
of bowel movements with large dose the PH of
the colon is reduced significantly causing a
decrease in the absorption of toxic
nitrogenous compounds with a subsequent fall
of blood ammonia in patients with hepatic
encephalopathy.
|
| Indications: |
Treatment of
chronic constipation.
Adjunctive treatment of hepatic
encephalopathy.
Disturbance of the intestinal bacterial
flora ( as in cases of long term treatment
of antibiotics ).
|
| Contra-indications: |
Patients with
galactosemia.
Intestinal obstruction.
|
| Precautions: |
Sedalac should
be given with caution in diabetic patients
as the syrup contains small quantities of
galactose and lactose
|
| Dosage and administration: |
Treatment of
constipation:
Adults: 3 teaspoonfuls 2-3 times daily
increased to 60 ml if necessary.
Children: Over 6 years: 1-2 teaspoonfuls
twice daily.
1-6 years: 1 teaspoonful twice daily.
Infants: Half teaspoonful twice daily.
Adjunctive treatment of
Hepatic encephalopathy:
Initially: up to 3 tablespoonfuls 3 times
daily then adjusted to the normal daily
dose.
|
| Side effects: |
Sedalac may
produce gaseous distension with flatulence
and abdominal discomfort such as cramping.
Excessive dosage may produce diarrhea,
nausea and vomiting .
|
| Warning: |
Keep your tablets in the pack in which they were
supplied.
Keep your tablets below 30°C.
Keep your tablets in a safe place where children cannot see or reach them.
|
| Packing: |
Bottle of 120
ml.
Bottle of 300 ml. |
