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Paracetamol
(Tablets and suspension)

Composition:
Each tablet contains:
Paracetamol 500 mg
Each teaspoonful ( 5 ml ) of suspension contains:
Paracetamol 120 mg

Properties:
Paracetamol reduces fever by direct action on the hypothalamus heat regulation center. Paracetamol is almost as potent as aspirin in inhibition of prostaglandin synthesis in the CNS, but its peripheral inhibition of prostaglandin synthesis is minimal.
Paracetamol exerts an analgesic effect by rising the threshold of response to pain stimuli. Generally the antipyretic & analgesic effects of paracetamol & aspirin are comparable, but paracetamol does not inhibit platelet aggregation.

Indications: Analgesic for pain, antipyretic and as antirheumatic too.

Contraindications:
Hypersensitivity to paracetamol .

Precautions: Paracetamol should be given with care to patients with impaired kidney or liver functions.

Side Effects:
When used as directed paracetamol rarely causes side effects however skin
eruptions or haematological reactions may occur.
Over dosage may produce symptoms such as vomiting, G.I.T disturbances, renal or liver affection.

Dosage and adminstration:
For adults:
One tablet every 4 hours, with maximum of 8 tablets daily.
For children:
Below 1 year : ½ teaspoonful every 4 - 6 hours.
1 - 3 years : ½ - 1 teaspoonful every 4 - 6 hours.
3 - 6 years : 1 teaspoonful every 4 - 6 hours.
6 - 12 years : 2 teaspoonfuls every 4 - 6 hours.
Daily dosage in children must not exceed 1.2 gm.

Overdosage:
Overdosage can result in sever liver damage & somtimes acute renal tubular
necrosis.
Activated charcoal may be given to reduce G.I.T absorption.
Treatment with acetylcysteine or methionine is essential, but charcoal is best
cleared from stomach first to prevent reducing their absorption.

Storage:
Keep at temp. not exceeding 30ºC.
Keep medicine out of reach of children.
Keep away from direct light.

Presentation:
Box of 1000 or 20 tablets.
Bottle of 60 ml or 120 ml

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