Composition:
Each tablet contains :
Griseofulvin ....................125 mg, 250 mg, 500 mg.

Properties:
Griseofulvin is the drug of choice for widespread or intractable dermatophyte infections. It is fungistatic against species of Microsporum Epidermophyton & Trichophyton.
The drug is well absorbed orally. The peak plasma level occurs at about 4 hours & ranges between 0.5 - 2 mcg / ml following a dose of 500 mg Griseofulvin.

Indications:
Dermatophyte infections of the skin,scalp, hair & nails.

Contraindications:
Hypersensitivity to griseofulvin, porphyria, hepatocellular failure and pregnancy.

Side effects:
Hypersensitivity reactions are the most common side effects. Nausea, vomiting, epigastric distress, headache, fatigue, dizziness, insomnia and
mental confusion may occasionally occur.

Precautions:
Photosensitivity reactions may occur, avoid prolonged exposure to sunlight or sunlamps.
Lupus erythematosus or lupus-like syndromes have been reported.

Drug interactions:
Griseofulvin may decrease the hypoprothrombinaemic activity of warfarin, patients may require anticoagulant dose adjustment.
Barbiturates usually depress griseofulvin activity, concomitant administration may require a dose adjustment of the antifungal agent.

Dosage:
Adults:
0.5 - 1 gm / day as single or divided doses with or after meals.
Children:
10 mg / kg body weight daily with or after meals.

Storage:
Keep at temp. not exceeding 30°C.
Keep medicine out of reach of children.

Presentation:
Box of 20 or 1000 tablets.