Composition:
Each Lyophilized ampoule contains
Adenosine triphosphate(ATP) …………. 10mg
Cocarboxylase …………………………... 50mg
Vitamin B12 ……………………………... 600mg
Nicotinamide …………………………….. 15mg
 
Each solvent ampoule contains
Lignocaine HCl ………………………….. 10mg

Properties:
► Adenosine triphosphate is concerned with the storage & release of energy, it has a fundamental role in biological
    transformation of energy; so it improves cardiac & peripheral circulation and hence it is used in coronary insufficiency. It also
    improves muscular power.
► Cocarboxylase the active form of vitamin B12 is indicated in many circulatory disturbances particularly when associated with
    cardiac dilatation. The neurotropic action of vitamin B12 is due to its capacity of promoting the utilization of circulating amino
    acids in nerve cells and the accumulation and/or synthesis of nucleic acid in the neurons.
► Nicotinamide regulates the process of phosphorylation and the metabolism of water and electrolytes.It has a
    pharmacodynamic effect on the cardiovascular system with special regars to the vasodilating action on the small vessels
    which account for the results often obtained in cases of embolism vasospatic headache and Raynaud's disease.

Indications:
► Toxic neuritis and neuropathies from diabetes and pernicious anemia
► Coronary heart disease, myocardis and myocariopathies.
► Neuralgia of various origins as trigeminal neuralgia.
► Myalgia and lumbago.
► Sciatica.
► Bursitlis and tendonitis.

Contraindications:
The drug is contraindicated in patients with known hypersensitivity to any of its components & in patients with a history of myocardial infraction, cerebral hemorrhage.

Precautions:
► If anaphylactic reactions followed administration of Adenosine injection have been occurred, do not administer further
    injection, and intermediately institute treatment for allergic reactions
► The drug should not be injected intravenously.

Use in pregnancy:
Safe use has not been established with respect to adverse effects on fetal development .Therefore the drug should not be used in women childbearing potential and particularly during early pregnancy unless the benefits out weigh the potential hazards

Use for children:
This drug is not recommended for children.

Dosage & route of administration & duration:
1-2 ampoules daily or as directed by the physician.
For reconstitution, inject the solvent into the lyophilized product ampoule and dissolve the mass thoroughly.
Inject intramuscularly immediately after reconstitution.

Adverse effects:
Flushing, dizziness and palpitations may occur, hypotension, dyspnea, epigastria discomfort, nausea, occasional local rash and diureses

Storage:
Keep at temp. not exceeding 30°C.
Keep medicine out of reach of children.

Presentation:
Box of 3 lyophilized ampoules+3 ampoules of solvent.