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Physician
Patient

 Anaphylaxis

 Anaphylaxis

Anaphylaxis is the most severe type of allergic reaction and requires immediate medical attention. If not treated right away, anaphylaxis may cause shock or death.
 
What happens during anaphylaxis?
People who have allergies have higher levels of the type of antibody known as Immunoglobulin E (IgE). The anaphylactic reaction depends on previous exposure or "sensitization" to a particular allergen. During the first exposure, the body builds up allergen-specific IgE antibodies.
Upon re-exposure to the allergen, the IgE antibodies launch a whole-body (systemic) immune response. This can result in rapid loss of blood pressure. The heart may strain, and the brain may stop receiving oxygen flow. The vocal chords and other tissues may swell. The lungs can fill with fluid, and the airways may become severely constricted.
 
What causes anaphylaxis?
Substances that can cause anaphylaxis include:
Latex
Insect sting , Venom
Immunotherapy solutions
Foods: particularly shellfish, peanuts, other tree nuts, eggs & milk
Medications: including antibiotics, general anesthetics, insulin, and progesterone , Vaccines that contain egg protein
 
Symptoms
Anaphylaxis usually occurs rapidly, unexpectedly, and affects many parts of the body.
Watch for the following symptoms:
Warmth, skin flushing, or hives
Tingling and swelling in the lips, feet, hands, or other body parts
Wheezing, whistling while breathing, or shortness of breath
Difficulty swallowing due to swelling in the throat
Lightheadness or faintness
Palpitations or irregular heartbeat
Loss of consciousness or seizures due to low blood pressure
Other symptoms may include hoarseness, cough, chest tightness, sneezing, and gastrointestinal symptoms like bloating, cramps, nausea, or vomiting.
 
Emergency treatment
Seek treatment of anaphylaxis immediately to re-open the airways and regain normal blood pressure.
Receive a shot of epinephrine, or other anti-inflammatory medications like corticosteroids or antihistamines.
Vital signs will be monitored for several hours after the reaction: anaphylactic symptoms can persist after treatment or return hours later.
 

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