Zestril
(Tablets)

Composition:
Each tablet contains:
Lisinopril..............................5 mg or 10 mg or 20 mg

Properties:
Lisinopril is an ACE inhibitor. It works by widening blood vessels, which makes it easier for the heart to pump blood through them, to all parts of the body. This helps to reduce raised blood pressure. It can also help the heart to work better if the heart does not pump as well as is needed.

Indications: “Zestril” is indicated for you if:
Your blood pressure is too high.
You have a heart condition. This means that the heart is not working as well as it did. This can make you feel breathless and tired after light exercise. You may also have swollen ankles and feet. “Zestril” may prevent your heart condition from getting worse.
You have had a heart attack (myocardial infarction). Although you have no symptoms at present, there is a risk that You may develop heart failure if your heart weakens further. “Zestril” may slow down or prevent the onset of heart failure.
You have a problem related to your diabetes.

Contraindications:
You must not take the tablets if you:
Are pregnant , or planning to become pregnant.
Are breast-feeding.
Have had an allergic reaction to “Zestril” or similar medicines (ACE inhibitors) in the past which has involved difficulty with swallowing or breathing, swelling to the hands, feet or ankles, face or lips, tongue or throat or if you or a member of your family has had a similar reaction for any other reason.
Are allergic to any of ingredients.
“Zestril” should not be given to children.
If you think that one of these apply to you, do not take the tablets. Tell your doctor and follow the advice given.

Precautions: You should also tell your doctor if you:
Know that you have a narrowing of the aorta (aortic stenosis), the kidney artery (renal artery stenosis) or an increase in the thickness of the heart muscle (hypertrophic cardiomyopathy, 'HOCM').
Have problems with your kidney or are undergoing dialysis.
Are on a low salt diet or you take potassium containing salt substitutes or supplements.
Suffer from diarrhea or vomiting.
Are going to have desensitization treatment (e.g. treatment to reduce the effects of an allergy to bee or wasp stings)
Have ever had an allergic reaction which involved difficulty with swallowing or breathing, swelling of the hands, feet or ankles, face or lips, tongue or throat.
Suffer from low blood pressure (you may notice this as fainting or dizziness).
Are having an operation, tell the dentist and the medical staff, especially the anesthetist that you are taking “Zestril”.

Drug interactions:
Your tablets are unlikely to affect your ability to drive or operate machinery. However, you should not perform such tasks, which need special attention, until you know how your medicine affects you.
Tell your doctor if you are taking any of these medicines :
Diuretics.
Other antihypertensive drugs.
Non-steroidal anti-inflammatory medicines (NSAIDs) such as Indomethacin (for arthritis or muscle pain).
Insulin or oral antidiabetic.
Lithium (for depression).

Dosage and administration:
You must keep taking “Zestril” even if you are feeling well, because regular treatment is most effective.
The dose you take will depend on your conditions and whether you are taking other medicines.
For high blood pressure: Treatment is usually started with a dose of 10 mg taken once a day. The dose is increased gradually until blood pressure is well controlled. The usual long-term dose is 10 to 20 mg taken once a day.
For a heart condition: Treatment is usually started with a dose of 2.5 mg taken once a day.
The dose is gradually increased to control the symptoms of heart failure. The usual long-term dose is 5 to 20 mg taken once a day.
After a heart attack: The usual dose is 5 mg on day 1 and 2, then 10 mg once a day.
For problems related to diabetes: Treatment is usually started with a dose of 2.5 mg taken once a day. The usual long-term dose is 10 to 20 mg taken once a day.
If you are taking “Zestril” for the first time you may feel light-headed or dizzy for a short time and it may help to sit or lie down. This is unlikely to happen when you are taking the tablets regularly. If you are worried, contact your doctor.
Take the tablets with a glass of water. This makes it easier to swallow.
Try to take your tablets at the same time each day-it will help you remember.
If you miss a dose, just carry on with the next dose when it is due. Do not take an extra tablet to make up.
If you take more than your normal dose, contact your doctor or nearest hospital.

Side effects:
“Zestril” is generally well tolerated, but like all medicines, can occasionally cause unwanted effects in some patients. Do not be alarmed at this list-you may not have any of them.

The most frequent undesirable events are dizziness, headache, diarrhea, cough, tiredness or nausea. Other possible but less frequent events include dizziness or light headedness when standing up quickly, dry mouth, fever, rashes (with or without itching), psoriasis, sensitivity to sun light, joint and muscle pain, weakness (loss of strength), pins and needless in the fingers and toes, impotence, changes in the way things taste, feeling sleepy or difficulty in going to sleep, strange dreams, running nose or sinus pain, vomiting, vertigo.

Rarely, other undesirable events may occur such as jaundice (yellow skin and / or eyes), the production of less or no urine, severe abdominal pain or indigestion, mood changes, confusion, wheezing, hair loss, sweating. Rarely there may be changes to some cells or other parts of your blood. It is possible that your doctor may occasionally take blood samples to check whether “Zestril” has had any effect on your blood; sometimes these changes may show themselves as tiredness or sore throat.

If you are diabetic and you have the symptoms of low sugar (hypoglycemia) whilst taking “Zestril”, you should tell your doctor.

You should stop taking "Zestril" and contact your doctor immediately if you begin to itch, get wheezy or have difficulty in breathing or swallowing, develop swelling of the hands, feet or ankles, face or lips, tongue or throat.

Tell your doctor or pharmacist if you notice any other troublesome effects which you think are related to the tablets.

Warning: Keep your tablets in the pack in which they were supplied.
Keep your tablets below 30°C.
Keep your tablets in a safe place where children cannot see or reach them.

Packing: Zestril   5mg   10 tablets.
Zestril 10mg   10 tablets.
Zestril 20mg   10 tablets.