Sedopram
(Tablets)    
  • Sedopram tablets
  • Composition:
    Each tablet contains:
    Citalopram Hydrobromide ............ Equivalent to 20 mg citalopram

Properties:
Citalopram is a selective serotonin reuptake inhibitor (SSRI) which plays an essential role in treatment of depression and other psychological disorders.
Citalopram is readily absorbed from gastro-intestinal tract, and maximum plasma concentrations are reached 2 to 4 hours after oral administration, and its protein binding is low.
Citalopram is metabolized by demethylation, deamination and oxidation to inactive metabolites. It is excreted in the urine and feaces.

Indications:
  • Mood Disorders: various degrees of depression,unipolar or dipolar mania, major or minor disorders
  • Neurotic disorders :as anxiety, phobia, and obsessive compulsive disorders (OCD)
  • Disturbed behavior & conduct disorders.
  • Eating disorders :anorexia nervosa, bulimia nervosa.
Contra-indications:
  • Hypersensitivity to the drug.
  • Concomitant use in patients taken monoamine oxidase inhibitors ( MAOI's )
  • Sever liver dysfunction.
  • Uncontrolled cases of diabetes or epilepsy and history of suicidal attempts.

Drug interactions:
Caution should be taken when the drug is taken in combination with somatriptan, warfarin, carbamazepine, omeprazole, cimetedine, metoprolol beta blocker , erythromycin and tricyclic antidepressants.

Precautions:
The drug should be used with patients with liver functions impairement, diabetes, epilespy and suicidal tendencies.

Use during pregnancy & lactation:
The drug is contraindicated during pregnancy and lactation.

Dosage and administration:
20 to 60 mg daily (the dose should be gradually increased from 20 mg according to the response of each dose)

Side effects:
  • Gastro-intestinal disturbances as nausea, vomiting, dyspepsia and diarrhea.
  • Anorexia and weight loss can be occurs.
  • Neurological side effects as insomnia, fatigue or tremors.
  • Sexual dysfunction may occurs.

Packing:
Box of 7 or 14 tablets.

Related Links

Serotonin and Sedopram (PowerPoint)