<| Composition: |
 |
Each tablet contains:
Citalopram
Hydrobromide............Equivalent to 20 mg
citalopram
|
| Properties: |
Citalopram is a
selective serotonin reuptake inhibitor (
SSRI ) which plays an essential role in
treatment of depression and other
psychological disorders.
Citalopram is readily absorbed from
gastro-intestinal tract, and maximum plasma
concentrations are reached 2 to 4 hours
after oral administration, and its protein
binding is low.
Citalopram is metabolized by demethylation,
deamination and oxidation to inactive
metabolites. It is excreted in the urine and
feaces.
|
| Indications: |
►Mood
Disorders: various degrees of depression,
unipolar or dipolar mania, major or minor
disorders
►Neurotic
disorders :as anxiety, phobia, and obsessive
compulsive disorders (OCD)
►Disturbed
behavior & conduct disorders.
►Eating
disorders :anorexia nervosa, bulimia
nervosa.
|
| Contra-indications: |
►Hypersensitivity
to the drug.
►Concomitant
use in patients taken monoamine oxidase
inhibitors ( MAOI's )
►Sever liver
dysfunction.
►Uncontrolled
cases of diabetes or epilepsy and history of
suicidal attempts.
|
| Drug interactions: |
Caution should
be taken when the drug is taken in
combination with somatriptan, warfarin,
carbamazepine, omeprazole, cimetedine,
metoprolol beta blocker ,erythromycin and
tricyclic antidepressants.
|
| Precautions: |
The drug should be used with patients with
liver functions
impairement,diabetes,epilespy and suicidal
tendencies.
|
| Use during pregnancy & lactation: |
The drug is contraindicated during pregnancy
and lactation.
|
| Dosage and administration: |
20 to 60 mg daily (the dose should be
gradually increased from 20 mg according to
the response of each dose)
|
| Side effects: |
►Gastro-intestinal
disturbances as nausea,vomiting,dyspepsia
and diarrhea.
►Anorexia and
weight loss can be occurs.
►Neurological
side effects as insomnia, fatigue or
tremors.
►Sexual
dysfunction may occurs.
|
| Packing: |
Box of 7 or 14 tablets.
|
|
Related Links |
Serotonin and
Sedopram (PowerPoint)
|
