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Sedopram
(Tablets)    

Sedopram tabletsComposition:
Each tablet contains:
Citalopram Hydrobromide ............ Equivalent to 20 mg citalopram

Properties:
Citalopram is a selective serotonin reuptake inhibitor (SSRI) which plays an essential role in treatment of depression and other psychological disorders.
Citalopram is readily absorbed from gastro-intestinal tract, and maximum plasma concentrations are reached 2 to 4 hours after oral administration, and its protein binding is low.
Citalopram is metabolized by demethylation, deamination and oxidation to inactive metabolites. It is excreted in the urine and feaces.

Indications:
Mood Disorders: various degrees of depression, unipolar or dipolar mania, major or minor disorders
Neurotic disorders :as anxiety, phobia, and obsessive compulsive disorders (OCD)
Disturbed behavior & conduct disorders.
Eating disorders :anorexia nervosa, bulimia nervosa.

Contra-indications:
Hypersensitivity to the drug.
Concomitant use in patients taken monoamine oxidase inhibitors ( MAOI's )
Sever liver dysfunction.
Uncontrolled cases of diabetes or epilepsy and history of suicidal attempts.

Drug interactions:
Caution should be taken when the drug is taken in combination with somatriptan, warfarin, carbamazepine, omeprazole, cimetedine, metoprolol beta blocker ,erythromycin and tricyclic antidepressants.

Precautions:
The drug should be used with patients with liver functions impairement, diabetes, epilespy and suicidal tendencies.

Use during pregnancy & lactation:
The drug is contraindicated during pregnancy and lactation.

Dosage and administration:
20 to 60 mg daily (the dose should be gradually increased from 20 mg according to the response of each dose)

Side effects:
Gastro-intestinal disturbances as nausea, vomiting, dyspepsia and diarrhea.
Anorexia and weight loss can be occurs.
Neurological side effects as insomnia, fatigue or tremors.
Sexual dysfunction may occurs.

Packing:
Box of 7 or 14 tablets.

Related Links
Serotonin and Sedopram (PowerPoint)
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