Sedobroxol
(Syrup)    
  • Sedobroxol Syrup
  • Composition:
    Each teaspoonful (5 ml) of the syrup contains:
    Ambroxol hydrochloride .............................. 15 mg
    Inactive ingredients:
    Sorbitol 70%,sodium benzoate, citric acid monohydrate, tutti fruitti flavor, purified water.
Properties:
  • Sedobroxol is a systemically active mucolytic agent.
  • Following orally administration, onset of action occurs after about 30 minutes.
  • The breakdown of acid mucopolysaccharide fibers makes the sputum thinner and less viscid and therefore more easily removed by coughing.
  • Although sputum volume eventually decreases, its viscosity remains low for as long as treatment is maintained.

Indications:
Treatment of respiratory disorders associated with viscid or excessive mucus (wet or productive cough): e.g.Tracheobronchitis, emphysema with bronchitis ; pneumoconiosis, chronic inflammatory pulmonary conditions, bronchiectasis, bronchitis with bronchospasm & asthma.

N.B.
During acute exacerbations of bronchitis it should be given with the appropriate antibiotic.

Contraindications:
Patients with hypersensitivity to the active ingredient (ambroxol hydrochloride), or to bromhexine, or to any of the ingredients in the formulation.

Precautions:
- Relative caution should be observed in patients with history of gastric or peptic ulcer.
- Use of Sedobroxol therapy is not recommended during the first trimester of pregnancy and breast-feeding mothers.

Dosage & route of administration  duration:
  • Sedobroxol should be administrated immediately after meals: One teaspoonful = 5ml
  • Adults & children (over 12 years old)
    10 ml (2 teaspoonful) to be administrated 3 times daily.
  • Children:
    Children 1-2 years
    ....... 2.5 ml (half teaspoonful) 2 times daily
    Children 3-6 years ........2.5 ml (half teaspoonful) 3 times daily.
    Children 7-12 years ......5 ml (one teaspoonful) 2-3 times daily.

Adverse effects:
Occasional mild gastrointestinal irritation and discomfort (e.g. diarreha; abdominal fullness and nausea)
Allergic reactions, primarily skin rashes , occur rarely.

Drug interactions:
Antibiotic concentrations (Amoxicillin, cefuroxime and erythromycin) in bronchopulmonary secretions and in the sputum are increased with concomitant administration of Sedobroxol.

Storage:
Keep at temp. not exceeding 30°C.
Keep medicine out of reach of children.

Presentation:
Bottle of 60 ml, 120 ml.