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Mebendazole
(Tablets , Suspension)

Composition:
Each tablet contains:
Mebendazole...............................100 mg.
Each 5 ml of the suspension contains:
Mebendazole..............................100 mg.

Properties:
Mebendazole, a benzimidazole carbamate derivative, is an anthelminthic with activity against most nematode and some cestode worms .It acts by irreversibly inhibiting glucose uptake by susceptible worms, resulting in depletion of the worm’s energy sources, glycogen and ATP.
Mebendazole is poorly absorbed from the GI tract. It is highly protein bound and undergoes extensive first - pass elimination, being metabolized in the liver, and is excreted mainly in the feaces.

Indications:
Treatment of intestinal nematode infections; Ascariasis, trichuriasis (round worm), entrobiasis (threadworm)‚ hookworm infections (ancylostomiasis and necatoriasis).
Treatment of mixed infections.
Treatment of hydatid disease.

Contraindications:
Mebendazole is contraindicated during pregnancy and lactation.

Precautions:
Patients receiving high doses of mebendazole, such as with hydatid disease‚ should be supervised closely.

Side effects:
Transient abdominal pain and diarrhea are very rare.
With very high doses, allergic reactions, raised liver enzymes values, may occur.

Dosage & route of administration & duration:
For Adults:
One tablet (100 mg) once in cases of entrobiasis.
One tablet (100 mg) twice daily for 3 days for Ascariasis, hookworm and trichuriasis .
For children over 2 years :
One teaspoonful ( 100 mg) in cases of entrobiasis.
One teaspoonful twice daily for 3 days for Ascariasis, hookworm and trichuriasis.

Storage:
Keep at temp. not exceeding 30ºC
Keep out of reach of children.

Presentation:
Box of 10 or 600 or 1000 tablets.
Bottle of 30 ml.

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