Magna-Biotic
(Tablets & Powder For Oral Suspension)
Composition:
Composition
Reconstituted Suspension
Tablets
156.25 mg / 5 ml
312.5 mg / 5 ml
375 mg/ tablet
625 mg/tablet
Amoxycillin
125 mg
250 mg
250 m
500 mg
Clavulanic acid
31.25 mg
62.5 mg
125 mg
125 mg
Properties:
Magnabiotic is
an oral antibacterial combination of
Amoxycillin & Clavulanic acid. Amoxycillin: Is a broad spectrum semi synthetic
penicillin . Clavulanic acid:
Is a B-lactam
structurally related to Penicillins that
inactivate B-lactamase enzymes commonly
found in micro-organisms resistant to
penicillin .
The combination of Amoxycillin
/ Clavulanic acid extends the antibiotic
spectrum of Amoxycillin to include bacteria
normally resistant to Amoxycillin & other
B-lactam antibiotics. Magnabiotic is wel
absorbed from G.I.T after oral
administration, stable in the presence of
gastric acid & may be administered with out
regard to to meals. About 50-70 % of
Magnabiotic is excreted unchanged in urine
during the first 6 hours after oral
administration . It diffuses readily into
most body tissues & fluids & can be detected
in middle ear effusion .
Contraindications:
A history of
allergic reactions to any Penicillin is a
contraindication.
Dosage & route of
administration & duration: ►Children:
9 months - 2 year :1/2 teaspoonful
Magnabiotic 156.25 mg every 8 hours .
2 - 7 year :1 teaspoonful Magnabiotic 156.25
mg every 8 hours .
7 - 12year:2 teaspoonful Magnabiotic 156.25
mg every 8 hours .
or teaspoonful Magnabiotic 312.5 mg every 8
hours .
►Adults: Mild to moderate infections : One tablet
Magnabiotic 375 mg every 8 hours.
Severe infections : One tablet Magnabiotic
625 mg every 8 hours.
Side effects:
Magnabiotic is
generally well tolerated. The majority of
side effects are mild & transient and
consist mainly of
diarrhea,
nausea,
abdominal discomfort, skin rashes &
urticaria which disappear upon
discontinuation of therapy.
Storage:
Keep in a cool
dry place at temp. less than 25ºC.
Keep medicine out of reach of children.
Presentation:
Bottle of 60 ml
or 80 ml of (156.25 mg)or(312.5 mg).
Box of 8, 10 tablets (375 mg) or (625 mg).