Should LIPONA (Atorvastatin) be administered at the
morning & before breakfast as the other members of
No, you can prescribe Lipona to be administered at
any time (day or night), before or after meals... as
Atorvastatin’s lipid lowering effect is not related
to time of administration or meals, unlike other
members of statins; Atorvastatin effects in serum
lipid lowering is attributed to the action of its
active metabolites rather than the parent drug, so
any decrease in plasma concentration or rate of
absorption will not affect its action.. This
advantage makes the administration of Lipona easier
for the patients.
What is the recommended dose of Lipona as a start in
The recommended starting dose of Lipona is one
tablet (10 mg) once daily, the dose should be
individualized according to baseline lipid profile &
Monitoring of lipid profile should be done after 4 –
6 weeks in order to assess the effective dose either
to continue with 10 mg or to increase the dose.
In more than 60 % of patients the 10 mg starting
dose is effective in achieving treatment goals
without any increase in the starting dose.