Fexofenadine hydrochloride...........120 or
Fexofenadine is a new
generation antihistamine which acts
selectively on peripheral H1receptors.
Fexofenadine is an active metabolite of terfenadine. it has rapid and long lasting
effect, with no sedative or ant cholinergic
effect. It is rapidly absorbed with peak
plasma concentration after 1_3 hour . it has
a half life of 11-15 hour. Fexofenadine
undergoes minor metabolism as its substance
is detected in urine and faeces.
Symptomatic treatment of
allergic disorders requiring
treatment with antihistamine (H1 blocker)
Sinusitis & other allergic
Hypersensitivity to Fexofenadine
Children under 12 years old.
Dosage & route of
administration & duration:
For adults and
children over 12 years old: One capsule
daily or as directed by physician.
containing aluminum and magnesium hydroxide
reduce absorption of Fexofenadine.
Erythromycin or ketoconazole increases the
level of Fexofenadine 2-3 times, but with no
effect on QT interval.
Omeprazole was found to have to have no
significant interaction with Fexofenadine
Preferably not to be used in
pregnancy, though extensive studies revealed
no teratogenic effect on animals.
Not recommended in lactating
nausea, dizziness, and fatigue may appear in
temperature not exceeding 30°C.
Box of 10
capsules 120,180 mg.