Each tablet contains:
Glimepiride...................1mg, 2mg or
Glimepiride is an oral
hypoglycemic drug of the Sulfonylurea class.
It lowers blood glucose levels by
stimulating the release of insulin from
functioning pancreatic beta cells & also by
increasing the sensitivity of peripheral
tissues to insulin.
Diabride is totally absorbed from the GIT
within 1 hour, with peak drug levels at 2 -
► Non insulin dependent
diabetes mellitus ( NIDDM) not responding to
diet & exercise alone.
► In combination with insulin in patients
whose glucose levels cannot be controlled by
diet, exercise, & oral hypoglycemic agents
► Hypersensitivity to the drug
► Diabetic ketoacidosis, with or without
► Hypoglycemia :
All sulfonylureas are capable of producing
hypoglycemia, proper patient selection,
dosage & instructions are important .
► Loss of
control of blood glucose, when a patient is
exposed to stress as fever, trauma,
infection, or surgery , loss of control of
blood glucose may occur. It should be
necessary to add insulin to Diabride or even
use insulin monotherapy.
pregnancy & Lactation :
not be used during pregnancy as it may cause
congenital abnormalities. It is also not
recommended to use during lactation. It is
advised that insulin be used during
pregnancy & lactation to maintain glucose
levels as close to normal as possible.
vomiting, gastrointestinal pain,&
have been rarely reported.
pruritus, erythema &
urticariaoccur in less
than 1 % .