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Baby Asp 75 mg
(chewable Tablets)

Composition:
Each tablet contains:
Acetyl salicylic acid ( Aspirin ).........................75 mg

Properties:
Acetyl salicylic acid has analgesic ‚ antipyretic and anti inflammatory properties .It inhibits prostaglandins biosynthesis by inhibition of cyclo - oxygenase enzyme, achieving these effects. It also has an antiplatelet action by inhibition of thromboxane A2 - an inducer of platelet aggregation on the arterial side of the circulation.

Indications:
Prophylaxis of cerebrovasular disease and myocardial infection.
Pediatric analgesic, antipyretic, juvenile arthritis.

Drug interaction:
NSAIDS : Avoid concurrent administration which results in increased side effects.
Anticoagulants : increase risk of bleeding due to antiplatelet effect.
Antiepileptic : enhanced effects of phenytoin and valoproate.
Corticosteroids : Increased risk of gastrointestinal bleeding and ulceration.
Antacids and adsorbents : excretion of aspirin increases in alkaline urine.
Cytotoxics : reduced excretion of methotrexate (increased toxicity(
Diuretics : antagonism of the diuretic effect of spironolactone, reduced excretion of acetazolamide (risk of toxicity
Metoclopramide : enhances the effect of aspirin (increased rate of absorption(

Contraindications:
Known hypersensitivity to Aspirin.
Hemophilia and other hemorrhagic disorders.
Children under 12 years (except cases of juvenile arthritis(
Gastrointestinal ulceration.
Pregnancy: Concerning the harmful effect of Aspirin in the last three months of pregnancy due to the possibility of prolonging the period of pregnancy and the increased risk of antepartum and postpartum hemorrhage as well as risk of bleeding tendency in the new born, it must not be used in high doses during the last 3 months of pregnancy
Breast feeding.

Precautions:
Acetyl salicylic acid should be taken cautiously in patients prone to dyspepsia or known to have a lesion of the gastric mucosa.
Renal & hepatic impairment.
Asthmatic patients.
G6 PD deficiency ( Glucose 6 phosphate dehydrogenase)

Dosage & route of administration & duration:
For Adults:
Cerebrovasular disease..................................................... 75 - 300 mg daily
Myocardial infarction.........................................................150 - 300 mg daily.
For children:
not less than 12 years (except juvenile arthritis).................. 65 mg / kg / daily.
N.B.: Aspirin must be taken after meals.

Adverse effects:
Gastrointestinal disturbances are the most common side effects.
Some persons especially asthmatics exhibit notable sensitivity to aspirin.
The drug increases the bleeding time, decreases platelet adhesiveness & in large doses, may cause hypo pro-thrombinemia.

Storage:
Keep at temp. not exceeding 30°C.
Keep medicine out of the reach of children.

Presentation:
Box of 2O tablets or 50 tablets.

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