Composition: |
Each
teaspoonful ( 5ml ) contains:
Terbtaline sulfate.................1.5mg
Each tablet contains:
Terbtaline sulfate.................2.5mg
|
 |
| Properties: |
Terbtaline sulfate is a
selective beta_adrenoceptor stimulant, with
selective bronchodilator action. It is more
selectively acting on the B2 _receptors of
the tracheal and bronchial smooth muscles
but its effect is relatively weak on the
B1_receptors of the heart; therefore
palpitations seldom occurs.
|
| Indications: |
|
| Bronchial
asthma, chronic
bronchitis,
emphysema, and other bronchopulmonary
disorders involving
bronchospasm. |
| Contraindications: |
Patients with hypertension, myocardial
insufficiency, and hyperthyroidism.
Patients sensitive to sympathomimetic
amines.
hypersensitivity to any of the constituents.
Sleep disturbances and behavioral effects
have been observed
|
| Drug
interactions: |
Beta blockers
especially nonselective e.g. propranolol may
partially or totally inhibit the effect of
beta stimulants so avoid concomitant use.
Use with caution in patients receiving other
sympathomimetics.
With corticosteroid : increased risk of
hypokalaemia.
Diuretic increased risk of hypokalaemia.
|
| Overdose: |
Possible
symptoms and signs: headache, anxiety,
tremors, tonic cramp, palpitations.
arrhythmias, fall in blood pressure.
Lab. Findings : hypokalemia and
hyperglycemia and lactic acidosis may occur.
|
|
Precautions: |
Care should be
taken in patients with previous history of
peptic ulcer.
Care should be taken in patients suffering
from myocardial in sufficiency or
thyrotoxicosis and in diabetic patients.
The drug is only used during pregnancy if
clearly needed.
Terbutaline sulfate excreted into breast
milk but effect on the infant is unlikely at
therapeutic
|
| Dosage & route of
administration & duration: |
Adults:
2 tablets 2-3 times daily.
Children:0.075-0.29 mg/ kg body
weight 3 times daily as follow:
|
Kg (Wt.) |
Dosage |
| 14
| 3.5 ml x 3
|
| 16 |
4 ml x 3 |
| 18 |
4.5 ml x 3 |
| 20 |
5 ml x 3 |
| 24 |
6 ml x 3 |
| 28 |
7 ml x 3 |
| 32 |
8 ml x 3 |
| 36 |
9 ml x 3 |
| 40 |
10 ml x 3 |
|
| Adverse
effects: |
In unusually
sensitive patients, tremor, headache,
tachycardia, palpitation, dizziness may
occur. These effects usually disappear
within the first week.
Potentially serious hypokalemia may be
observed. Sleep disturbances and behavioral
effects have been observed in children.
|
| Storage: |
Keep at temp.
not exceeding 30°C.
Keep medicine out of reach of children.
|
| Presentation: |
Syrup: Bottle of 120 ml.
Tablets: Box of 20 tablets.
Box
of 1000 tablet
|
